What happens if you give drugs to spiders

Many people are familiar with the effects of LSD and psychotropic drugs on spiders. What many people are NOT familiar with is the effect of caffeine on spiders.

Caffeine theoretically was evolved for use as an insecticide.

Normal Spider, no caffeine

Spider exposed to LSD

Spider exposed to marijuana

Spider exposed to Caffeine

As you can see, the spiders reacted similarly to the drugs given. One of the most startling effect was caffeine. Given a completely colloquial assertion, I'd say that the spider looks incredibly tired and disoriented in the caffeine web.

(Please see Spider Communication: Mechanisms and Ecological Significance
Edited by Peter N.Witt & Jerome S. Rovner - Princeton University Press -1982)